The first and only vaccine conditionally licensed to reduce the amount of E. coli O157 pathogens in the intestines of cattle.
The Escherichia Coli Bacterial Extract vaccine is for use in healthy cattle 5 months of age or older to reduce prevalence of the E. coli O157 carrier state, and for reduction in the amount of E. coli O157 shed in feces to minimize E. coli O157 exposure and infection of herd-mates. This product is conditional. Efficacy and potency test studies are in progress.
Please contact your Pfizer Animal Health representative
or call 800-733-5500 to learn more.
Key Benefits
Now there’s a weapon in the battle against Escherichia coli (E. coli) O157 that you can use prior to harvest. Escherichia Coli Bacterial Extract vaccine* with SRP® technology is the first and only vaccine approved by the USDA to reduce the amount of E. coli O157 pathogens in the intestines of cattle.
Why should I be concerned about E. coli in beef?
No matter what segment of the beef industry you’re in, we’re all in this together; fighting a common enemy that threatens the livelihood of each and every person connected with our business. And together, we’re committed to doing all we can to help reduce the threat of E. coli O157 contamination in beef. Why? Because contaminated beef can lead to sick consumers.
E. coli bacteria are members of a large group of bacterial agents that can inhabit the lower intestinal tract of cattle. Most strains are normal inhabitants and do not cause disease in cattle. However, some are pathogenic, or disease causing, when human infections occur, causing serious illness and even death in people. The Centers for Disease Control and Prevention (CDC) estimates that every year at least 63,153 Americans are infected, and of those, 2,138 are hospitalized and about 20 die as a direct result of E. coli O157 infection and its complications.1
Efficacy
Escherichia Coli Bacterial Extract vaccine with SRP technology has been shown to reduce the number of cattle testing positive for the bacteria by 85 percent.2 And those animals still testing positive show a 98 percent reduction in concentration of E. coli O157.
1Scallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson M-A, Roy SL, et al. Foodborne illness acquired in the United States — major pathogens. Emerg Infect Dis. 2011 Jan; [Epub ahead of print]
22Thomson DU, Loneragan GH, Thornton AB, Lechtenberg KF, Emery DA, Burkhardt DT and Nagaraja TG. Use of a siderophore receptor and porin proteins-based vaccine to control the burden of Escherichia coli O5157:H7 in feedlot cattle. Foodborne Pathogens and Disease 2009;6:871-877.
Dosing & Administration
Shake well before use. Administer 2 mL (1 dose) subcutaneously. Revaccinate in two to four weeks and again at least six weeks after the initial dose to complete the initial vaccination program. Revaccinate annually. Use entire contents once opened.
Resources & Technical Information
Store at 35° to 45°F (2° to 7°C). DO NOT FREEZE. Use entire contents when first opened.
Do not vaccinate within 60 days of slaughter.
Transient swelling at the injection site is commonly observed.
Do not vaccinate within 60 days of slaughter. In case of allergic response, administer flunixin meglumine and/or epinephrine.
Contains emulsified adjuvant. In case of self-injection, seek immediate medical attention.
*This product license is conditional. Efficacy and potency test studies are in progress.
Technical inquiries: 800-366-5288
*This product license is conditional. Efficacy and potency test studies are in progress.
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